Signs of Low Testosterone

Signs of Low TestosteroneTestosterone is one of the hormones produced in the human body. Testosterone is especially important for men, as it is responsible for their sexual ability, muscles, and overall body weight. Levels of this hormone usually sink when men get older. However, should they decrease too fast, a man can experience a variety of rather unpleasant symptoms. If you’ve been diagnosed with low-T, you might want to find out more about medicines that treat this condition by going to this website:

However, if you’re still in doubt whether your body is still producing sufficient amounts of testosterone or not, check yourself for the following symptoms:
Low libido and weak erection. Testosterone is produced in male testicles, and it is partly responsible for their normal function. Men with low-T may find themselves lacking in sexual drive and unable to develop and maintain a strong erection.
Weight gain and muscle loss. Low testosterone levels are often responsible for excessive amounts of fat stored in a man’s organism, as well as changes in its distribution around the body. Men with low-T sometimes develop abnormally large breasts, for instance. Low-T also affects muscles, weakening them and preventing new muscle building.
Fatigue and depression. Low testosterone can cause men to feel constantly tired, even if they have a healthy lifestyle and get enough sleep. What’s more, it can also lead to anxiety, inability to concentrate and quickly changing moods.
Hair loss. Even though going bald as you get older is quite common for men, those with low-T can also experience a decrease in the amount of facial and body hair.
Osteoporosis. Testosterone also affects the bones, so men whose bodies are unable to produce enough of this hormone might experience bone mass loss. This often leads to fragile bones, which are easy to damage, especially in older men who have lived with low-T levels for a long time.

How Long Do Hemorrhoids Last? Learn These Factors

How Long Do Hemorrhoids Last - Learn These Factors

We already know that there are basically two types of hemorrhoids. They can be either internal hemorrhoids or external hemorrhoids. Of course, each of them is caused by different factors, has different signs and symptoms, and requires different treatment. Many people, sufferers and health professionals, are talking about “how long do hemorrhoids last?” and this will be different between the internal and external hemorrhoids.

First, you need to differentiate the internal hemorrhoids from the external one. If you find rectal draining, but don’t feel pain, you might have internal hemorrhoid. Internal hemorrhoid exists far inside the rectum and can’t be seen. Unlike the internal one, the external hemorrhoid can cause some pains and can be seen because it is just outside the rectum. How long do hemorrhoids last? Unfortunately, one can’t determine how long it lasts for each type of hemorrhoids because they may not be healed without treatment, especially when they severe.

How Long Do Internal Hemorrhoids Last and What Makes It Long?

There are several ideas about how long do hemorrhoids last as explain in freehemorrhoids, especially for the internal hemorrhoids. One says that hemorrhoids do not always respond to topical suppositories or ointments. Sometimes, hemorrhoids need direct injection for straight treatment. Thus, they can last in a long time. Another similar opinion shows that the internal hemorrhoids can last pretty long time. Luckily, they sometimes don’t cause pains, but when it hurts, one should talk to doctor to give further treatment. In conclusion, what makes the internal hemorrhoids last long is its less painful health problem so that some sufferers do not realize that they actually have them.

How Long Do External Hemorrhoids Last and What Makes It Longer?

There are also several opinions about how long do hemorrhoids last, especially for the external one. Mostly, the external hemorrhoids subside in a few days. However, some bouts may also last as long as 2 weeks. This can be longer if one has suffered with the external hemorrhoids before. Then, the external hemorrhoids that have already developed a blood clot commonly take around 3 weeks to 3 months to heal. The time depends on the size, severity and the treatment that is taken.

Factors Influencing How Long Do Hemorrhoids Last

In addition to the types of hemorrhoids that may differentiate the time to heal this problem, there are also several other factors that influence how long do hemorrhoids last. The first factor is whether you are pregnant or not. Pregnancy will make the hemorrhoids a bit more difficult to heal. How long do hemorrhoids last in pregnancy may be longer than the hemorrhoids in not-pregnant women. Therefore, pregnant women should have high fiber diet and at least 8 glasses of water every day.

The other factor influencing is sedentary job. Just because one has a sedentary job does not mean that they may take less water. They should drink water as much as those with active jobs. With enough water, body will not get water from bowel, duodenum or urinary tract so that this will improve the hemorrhoids. Enough intakes of fresh fruits, vegetables and water are highly recommended for those who have hemorrhoids. How long do hemorrhoids last? Everything has been clear here.

3 further types of cancer clinical trials

Medical research takes many forms and within the cancer research domain, there are a range of clinical trials taking place at any one time to help develop new drugs. Here we look at three further types of cancer clinical trials – prevention trials, trials that focus on causes and patterns, and sequential trials.


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Prevention trials

Participants in prevention trials are helping to see if a specific drug or form of treatment can prevent a type of cancer from developing in the first place, rather than focussing on a cure. Therefore, those involved in the trial won’t have cancer, but they could come from a high risk group or just be part of the general population.

The IBIS 2 breast cancer trial is an example of such a prevention programme. This involved a large group of post-menopausal women who had a particularly high risk of developing breast cancer, to see if the drug anastrozole was beneficial in preventing the cancer developing. The results showed that those taking the drug were 53% less likely of developing the cancer than the participants that took the placebo.

Causes and patterns of cancer

Trials that investigate the possible causes or patterns of cancer are called epidemiology studies and the majority of these involve observational studies. These can be cohort studies where a group of people are followed for a length of time to see if they develop cancer, with the particular risk factors then being examined.

Case control studies assess those who already have the disease against those who don’t, to see if they were exposed to specific risks.

The other types of studies are cross-sectional, which are conducted over a short space of time and look at links between risk factors and those who have cancer.

Once trials have been completed, drugs have to be reviewed by the relevant body, such as the FDA, and there are companies to help with FDA 510k submissions such as fdathirdpartyreview.

Sequential trials

The other type of cancer trial is sequential. These are beneficial as they require fewer participants and results can be shown earlier, as they are worked out throughout the trial instead of just at the end. Participants are treated sequentially in a specific group, with each group given a different dose or in a different way to see which gives the best results.

Human growth hormone


Hormones are the chemical messengers of the body that stimulate a tissue to put it into specific actions. There are many hormones secreted in our body and they are secreted by various glands. Further more the glands are also of two types- exocrine and endocrine glands. While the secretion of the exocrine gland is secreted outside the body for e.g. tear by lacrimal gland, saliva by salivary gland, etc., endocrine gland secretion is secreted inside the blood directly which acts directly on the target organs. The endocrine glands in the body are pituitary, thyroid, pancreas, adrenal, testes, ovary and parathyroid gland. While the hormones of the glands are very essential for the normal functioning of the body, the secretion of the glands are controlled by the pituitary gland which is called as the master gland.

One of its secretions is the human growth hormone which is responsible for the growth of the body parts. Secretion of this hormone is maximum during the adolescence as it is time when the physical as well as mental development of an indignant takes place. After the body reaches a stage of full growth, its secretion starts declining. So now people have claimed that if this hormone is administered in the body in the form of injections, then it produces an anti-ageing effect and also build up muscles which enhance the appearance.

There are many products available in the markets which are a form of human growth hormone or somatotropin. HGH is being sold in the market by many brand names and you can read more about them at They are now being used by many people to grow their muscles in desired form and also produce anti-ageing effects. However the genuineness of the products should be cross checked properly. It should also be noted that genuine products are available in the forms of injections and not pills or sprays so any company that claims that they are selling the drug in the form of a pill or spray should be investigated properly.

Weight loss regimes


In the recent times, due to our sedentary lifestyles, unhealthy eating habits and less physical work outs, we have to deal with a number of problems like lifestyle disorders and weight gain. If we manage our weight scientifically, then we will be able to manage many health related problems. We often try various remedies like joining a gym, changing our diets etc.

So the big questions is how to lose weight effectively and how should we start dieting.

If we manage to reduce the junk food and the excess carbs from our diet, then certainly we will be able to reduce our weight. However, most of the people do not take this seriously, they stat the regime seriously but often get distracted and get back to their older junk routines. It is actually little difficult to reduce the carbs, hence it is a big question as to how will we reduce our weight and what should we take for in between meals. The answer is that when we decide to reduce the carbohydrate intake, then we should replace the carbohydrate by proteins, which will satiate our hunger and contain essential nutrients for good health. There are MRP shakes available in the market that act as meal replacement shakes. They have the high protein content which is essential for development of lean muscles and also cuts the unnecessary fat intake. They also contain some good forms of carbs that release the energy throughout the day and thus keep you satiated. They are rich in essential amino acids and also contain the dietary fibres which are important for cleansing the gut.

Hence see that we have a good remedy for weight loss in the form of MRP shakes. Also working out is very important. Now when we think of cutting the carb and keeping ourselves hungry for entire day, we will end up harming our body because by staying hungry, we will not get the nutrients essential for keeping our body working.

Nifedipine tablets

nifedipine 30 mg tablets

What is Nifedipine and what is it used for?

Nifedipine is a specific drug used for the treatment of hypertension, as it belongs to the pharmacological class of calcium channel blockers. It has greater functionality on dilation of the arteries, compared to other calcium channel blockers. In fact, it is used for the short-term treatment for various types of angina (in particular in angina pectoris vasospastic or Prinzmetal’s angina)

The modified-release tablets have a hole performed in the compressed membrane with laser technology (OROS technology, osmotic pump used for oral sustained release): the hole allows the controlled and constant release of the active substance, producing benefits both in the treatment of hypertension and of angina pectoris.

Nifedipine, when administered orally, is absorbed by the body very rapidly and almost totally by the intestines, so sudden to guarantee a maximum plasma peak in 30/60 minutes. Although the absorption is very high, bioavailability is approximately around 50% considering the first passage effect characterized by the oxidation and the subsequent inactivation of the active substance. The biological active quota, acts on the surface of the smooth-muscle cells by inhibiting the activity of the active calcium channels. Those channels are responsible for the massive entrance of calcium in the intracellular environment, which is necessary to guarantee al the events that underlie the cell’s contraction.

The muscle relaxant action takes place on a fibro cellular level in the coronary arteries, while the cardiac and skeletal muscles aren’t involved in the process.

The biological action of Nifedipine does translate in vasodilation and decrease in peripheral resistances, with a subsequent reduction of the arterial pressure, the cardiac workload and the request of oxygen.

When the action of Nifedipine is ended, after 2-3 hours, the active substance is removed through the renal pathway.

What you have to know before taking Nifedipine

The administration of Nifedipine needs to be done with particular attention when the patient is following a medical therapy that includes the use of antihypertensive drugs or when the patient suffer from hypotension.

A monitoring of the glycemic levels is essential when Nifedipine is administered to diabetic patients, and in case of hyperglycaemia, is advisable to suspend the therapy.

Also, the dosage of Nifedipine needs to be reviewed when the patient suffer from hepatic impairment, considering the first passage effect which halve the biologically efficient dosage, while a suspension of the therapy needs to be done gradually in order to avoid rebounds.

Severe blood pressure losses, adaption reactions to the therapy (at his initial phase) and the individual sensitivity to Nifedipine, could make the usage of machineries dangerous as well as driving.

It’s important to note how the concomitant assumption of other drugs may alter Nifedipine’s pharmacological properties, so it’s highly advised to consult the specialist if the patients is following another medical treatment.

The side-effects of Nifedipine

The clinical trials shows a good tolerability of the product, with not-so-relevant and transitional adverse reactions.

The side-effects of Nifedipine may include:

  • Headache
  • Nausea
  • Dizziness
  • Warmth sensation
  • Heartburn
  • Increased heart rate
  • Muscle cramp
  • Constipation
  • Cough
  • Sexual related issues

Suggested dosage for Nifedipine

For arterial hypertension and during the treatment of ischemic heart diseases and Raynaud’s syndrome, usually it’s advised to take one capsule for three times a day. Even though this is the suggested dosage for Nifedipine, the therapy is subjected to significant variations in terms of useful and effective dosage. For this reason, the dosage needs to be personalized by the specialist, based on the individual needs of the patient and on the severity of the ongoing disease.

The assumption of Nifedipine needs to be done on an empty stomach, because pharmacokinetic studies showed how food might increase the time required for the plasma peak to reach its maximum.

For more information on Nifedipine 30 mg OROS tablets consult website.

3 Reasons for Hiring a Live In Caregiver

3 Reasons for Hiring a Live In Caregiver

Instead of sending your ageing loved one to a nursing home, it is better if you hire a live in caregiver. It might be a bit costly, but it is a much better option. You will get more services and you are assured that this person will provide the one you love with the kind of assistance deserved. If you are not yet convinced, here are some other reasons why you should hire a caregiver.

  1. Companionship

Ageing patients might not necessarily have severe medical conditions that have to be taken care of frequently. Some of them simply need someone to talk to. Since you can’t be there full time due to the nature of your job, it is best if you hire someone to serve as their companion. However, it does not mean you are freed of your duties to the person you love. After all, nothing beats the time spent with family.

  1. Immediate medical assistance

Seniors are no longer able to do some tasks on their own. They need someone to assist them. They might not have the capacity to walk on their own or eat without being fed. This is what live in caregivers can provide. They are also those with medical needs. There should be someone to look after them at all times, to call for an ambulance or more medical help in times of crisis. Their chances of survival are much better if someone is there by their side all the time.

  1. Some chores

Even if you are there at home, you might not provide everything that your loved ones need. You have to juggle a lot of other tasks. There are times when you can’t even buy the items necessary for the home. You can count on the live in care giver to help out with some tasks. You can ask this person to go to the grocery store or to cook simple meals. As long as these tasks are not frequently done and they don’t have much on their hands, you can ask them to provide this type of service.

These are just some of the reasons why live in care is necessary. You have to invest in this service because you love your family. You have been given love, affection and care when you were younger. It is high time for you to give back what you have been shown before. Hiring someone to provide care for ageing family members is just one way to do so. You want their last years to be memorable. You want them to feel loved up until the end of their lives.

Image: (Praisaeng)